Wells has been plagued by a turf toe injury and has only been able to play in three games for the Cardinals this season. The fourth-year back has been out of action since the team's 27-6 win over the Philadelphia Eagles on Sept. 23. Wells get the start despite a stellar game from running back LaRod Stephens-Howling on Sunday.
Cornerback Patrick Peterson, who left the Cardinals' 23-19 loss to the Atlanta Falcons with cramping in his hamstring is expected to be a full participant in the team's practices this week.
Quarterback Kevin Kolb is working to come back from a concussion, and could make head coach Ken Whisenhunt's decision on a starting signal caller a little more difficult following the benching of John Skelton for rookie Ryan Lindley last Sunday.
Kickoff is scheduled for 2:25 p.m. MT at University of Phoenix Stadium on Sunday and the game will be televised on FOX.