The Arizona Cardinals managed only two first quarter field goals and Rams' running back Steven Jackson scored in the fourth quarter on a 27-yard run, leading to a 19-6 loss to the NFC West-leading St. Louis Rams. The Rams kept pace with the Seattle Seahawks, who beat the Carolina Panthers 31-14, evening their record at 6-6 and keeping themselves in the NFC playoff picture. Jackson rushed for 102 yards and rookie Sam Bradford threw 187 yards and an interception, on 18/29 passes.
In a losing effort, Tim Hightower ran well, gaining 81 yards on 15 carries. But the story was the inability of the Arizona offense to score points. Starter Derek Anderson started well, but could not find the end zone and was intercepted once. He was pulled from the game in the second half, finishing 7/20 for only 93 yards.
Max Hall replaced him, but injured his shoulder recovering his own fumble, and he left the game after completing 1/3 passes and a pick. Rookie John Skelton finished the game and made a couple of decent throws. He finished 3/6 for 45 yards.
Larry Fitzgerald tied the franchise record for career catches with four in the game, but could not find the endzone, so he remains three TDs away from the team record for receiving scores.
With their seventh consecutive loss, the Cardinals assured themselves that they will end with a losing record for the first time since Ken Whisenhunt became their head coach.