The only time the Ducks didn't lead was the first 12 seconds of the game as De'Anthony Thomas ran back the opening kickoff 94 yards for the touchdown. A Dion Jordan two-point conversion run made it 8-0 and the Ducks never looked back. Down 15-0 and looking shell shocked in the first quarter, the Wildcats responded, scoring 10 straight points to start the second quarter on a Collin Klein touchdown run and Anthony Cantele field goal. The Wildcats looked to have momentum going in to halftime before freshman quarterback Marcus Mariota led the Ducks 77 yards in just 46 seconds to give Oregon a 22-10 lead going in to the half.
The Ducks continued to pour it on in the second half, scoring 10 points in the third quarter before the Wildcats answered with an early touchdown at the start of the fourth quarter. Oregon tacked on a field goal to make it 35-17 before intercepting Klein to seal the victory.
Mariota was named the game's MVP, finishing with 166 yards and two touchdowns in the air and 62 yards and one touchdown on the ground. Klein, a Heisman finalist, finished with 151 yards, one passing touchdown and two interceptions. He also added 30 yards and a touchdown on the ground.