Boston, MA (Sports Network) – Dustin Pedroia and Kevin Youkilis each hit a two-run homer to lead Boston over Arizona, 6-2, in the second of a three-game interleague set from Fenway Park.
Adrian Beltre and J.D. Drew also knocked in a run apiece for the Red Sox, who have won two in a row to start the series and four of five overall.
Jon Lester (8-2) turned in seven solid innings, allowing just four hits and two runs while fanning seven with three walks. The lefty, who earned his 50th career win, has not lost since April 18, gaining eight positive decisions in 11 starts since then.
Jonathan Papelbon was credited with his 15th save after coming in for the final out.
Justin Upton slugged a two-run homer for the D-Backs, who slid to their fourth defeat in six contests and lost their franchise-record 12th straight road game.
Rodrigo Lopez (2-6) dropped his fourth straight decision after yielding 10 hits and six runs over seven full frames.
The Sox hit the board in the first as Marco Scutaro stroked a leadoff single and Pedroia followed with a two-run shot over the Green Monster. Upton countered with his own Monster shot in the second with Chris Young on base to tie the game.
Boston came back to make it 4-2 the home third, as Drew hit an RBI double and Beltre followed with a run-scoring single with two down.
Lester worked out of a bases-loaded jam in the fourth by getting Chris Snyder on a fly out to left, then got around a leadoff walk to Kelly Johnson in the fifth by retiring the next three batters.
Three more Arizona men were turned aside by Lester in the sixth, and he finished his outing by getting three in a row after plunking Rusty Ryal in the seventh.
In the home portion, David Ortiz singled with two down and Youkilis followed by hitting the left-field seats for a 6-2 score.
Daniel Bard took over in the eighth and retired the side in order. Ramon Ramirez allowed a walk to Miguel Montero and a single to Upton before retiring the next two batters.
Papelbon was called on, and though Upton moved to second on defensive indifference to put two in scoring position, Johnson lofted a harmless fly to left to end the game.
Lester improved his career mark to 50-18 in 106 games (105 starts)…The Red Sox have won six of the last eight meetings with the Diamondbacks since 2007…Scutaro, Beltre and Pedroia all finished with two hits for Boston…Upton was the lone Arizona batter with more than one hit.