In perhaps the greatest indication of the Tigers' mounting injury woes, the line for tonight's clash between No. 23 Arizona State and No. 19 Missouri has now moved to make the Sun Devils a full 10 point favorite.
The opening line was 6.5 in favor of ASU, a figure that raised some eyebrows, given the Tigers' rank and 22-game non-conference winning streak.
However a rash of key injuries combined with their lackluster 17-6 victory over Miami of Ohio last week have cast further doubt in the linemaker's heads on Missouri's chances.
They will be without two starting offensive linemen in left tackle Elvis Fisher and center Travis Ruth, their starting running back in Kendial Lawrence and their best deep threat in wide receiver Jerrell Jackson. However, the injuries may be most evident on defense, where the Tigers will try to slow the Sun Devil offense without All-Big 12 defensive end Jacquies Smith and linebacker Will Ebner
The action kicks off at Sun Devil Stadium at 7:30.