The Arizona Cardinals elected to defer when they won the coin toss before the game, hoping the defense would make a statement early against the Buffalo Bills. They did, as Daryl Washington forced Fred Jackson to fumble on the first play from scrimmage to give the Arizona the ball right away.
After only three plays, they were forced to kick a field goal, but Jay Feely hit the 49-yarder to take a 3-0 lead.
The Buffalo offense would be forced to punt on the next series, but the Cardinals put together another terrible drive. A negative run came on first down and a penalty on second down led to Kevin Kolb getting sacked in the end zone for a safety.
When Buffalo got the ball back after the free kick, they promptly marched down the field in 10 plays, mixing runs and passes, with C.J. Spiller running in the touchdown from 10 yards out.
Arizona amassed a total of 14 yards of offense in the first quarter, with only one pass play going for positive yardage -- a 24-yard play to Michael Floyd.
Buffalo held the ball for nine and a half minutes of the first quarter. Fred Jackson has 25 yards rushing and C.J. Spiller has 19 for the the Bills.